Research has shown that cancer cells can survive chemotherapy through autophagy. This ability allows cancer to reoccur after chemotherapy.
Autophagy is the process of certain organelles breaking down unnecessary cellular components for energy in times of low energy or a hostile environment. During chemotherapy, it is possible for cancer cells to have higher levels of autophagy than normal, and in those cases, the cell can recover and divide.
This has important implications for the future treatment of cancer. It tells doctors more about how cancer cells can recover, and it also advances our ability to treat cancer. A medication that inhibits autophagy while a patient is undergoing chemotherapy would make the cancer much more vulnerable to the chemo.
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